TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments
The RNA binding protein TRBP is a component of the Dicer complex but its role in microRNA biogenesis remains poorly understood. Here the authors use a crowded RNA environment and single-molecule imaging to show that TRBP acts as a gatekeeper to prevent Dicer engagement with pre miRNA-like substrates...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Portfolio
2016-12-01
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| Saila: | Nature Communications |
| Sarrera elektronikoa: | https://doi.org/10.1038/ncomms13694 |
| Etiketak: |
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