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Model of ligand-triggered information transmission in G-protein coupled receptor complexes

We present a model for the effects of ligands on information transmission in G-Protein Coupled Receptor (GPCR) complexes. The model is built ab initio entirely on principles of statistical mechanics and tenets of information transmission theory and was validated in part using agonist-induced effecto...

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Bibliografische gegevens
Hoofdauteurs: Roger D. Jones, Alan M. Jones
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2023-05-01
Reeks:Frontiers in Endocrinology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fendo.2023.1111594/full
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