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The role of orphan G protein-coupled receptors in pain

G protein-coupled receptors (GPCRs), which form the largest family of membrane protein receptors in humans, are highly complex signaling systems with intricate structures and dynamic conformations and locations. Among these receptors, a specific subset is referred to as orphan GPCRs (oGPCRs) and has...

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Principais autores: Chengfei Xu, Yahui Wang, Huadong Ni, Ming Yao, Liang Cheng, Xuewu Lin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-04-01
Serier:Heliyon
Fag:
G protein-coupled receptor
Orphan G protein-coupled receptor
Pain
Endogenous ligand
Monoclonal antibody
Rodents
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844024048497
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