Distinct type of transmission barrier revealed by study of multiple prion determinants of Rnq1.
Prions are self-propagating protein conformations. Transmission of the prion state between non-identical proteins, e.g. between homologous proteins from different species, is frequently inefficient. Transmission barriers are attributed to sequence differences in prion proteins, but their underlying...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2010-01-01
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| Schriftenreihe: | PLoS Genetics |
| Online-Zugang: | http://europepmc.org/articles/PMC2809767?pdf=render |
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