Conformational diversity in purified prions produced in vitro.

Prion diseases are caused by misfolding of either wild-type or mutant forms of the prion protein (PrP) into self-propagating, pathogenic conformers, collectively termed PrPSc. Both wild-type and mutant PrPSc molecules exhibit conformational diversity in vivo, but purified prions generated by the ser...

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Үндсэн зохиолчид:	Daniel J Walsh, Abigail M Schwind, Geoffrey P Noble, Surachai Supattapone
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2023-01-01
Цуврал:	PLoS Pathogens
Онлайн хандалт:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011083&type=printable
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!