Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

ABSTRACT Immune checkpoints, the key gatekeepers of immune homeostasis, have become the central targets of modern cancer immunotherapy. These regulatory pathways, composed of co‐suppressive and co‐stimulatory molecules, enable the immune system to distinguish between self and non‐self while preventi...

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Detalhes bibliográficos

Principais autores:	Han Sun, Dan Huang, Huiling Zhang, Mingyuan Dong, Simiao Wang, Man Sun, Jiayi Liu, Yiqi Wang, Xiaojie Qu, Xuefeng Li, Zhaogang Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-09-01
coleção:	MedComm – Oncology
Assuntos:	immune checkpoint immune escape immunotherapy monoclonal antibody
Acesso em linha:	https://doi.org/10.1002/mog2.70030
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