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Macrophage-centered immunotherapy for osteosarcoma: mechanisms, repolarization, and translational strategies

Abstract Despite multimodal treatment strategies, survival rates for osteosarcoma have remained stagnant, and immune checkpoint blockade targeting PD-1/PD-L1 alone has demonstrated limited clinical benefit. Tumor-associated macrophages (TAMs), which are abundant in osteosarcoma and predominantly exh...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Zhide Li, Dong Lin, Liandi Wu, Wending Xu, Haibo Zhang, Zhaonong Zhuang, Long Zhang, Jianan Chen, Zhaoyuan Su
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-03-01
Rangatū:World Journal of Surgical Oncology
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12957-026-04288-5
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