Macrophage-centered immunotherapy for osteosarcoma: mechanisms, repolarization, and translational strategies
Abstract Despite multimodal treatment strategies, survival rates for osteosarcoma have remained stagnant, and immune checkpoint blockade targeting PD-1/PD-L1 alone has demonstrated limited clinical benefit. Tumor-associated macrophages (TAMs), which are abundant in osteosarcoma and predominantly exh...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , |
|---|---|
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BMC
2026-03-01
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| سلاسل: | World Journal of Surgical Oncology |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s12957-026-04288-5 |
| الوسوم: |
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