Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms
The development of inhibitory antibodies to factor VIII is the most serious complication of replacement therapy in hemophilia A. Activation of the innate immune system during exposure to this protein contributes to inhibitor development. However, avoidance of factor VIII exposure during innate immun...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2018-08-01
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| coleção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/8562 |
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