Comparison of the immunogenicity of different therapeutic preparations of human factor VIII in the murine model of hemophilia A

Von Willebrand factor (VWF) has been proposed to reduce the immunogenicity of therapeutic factor VIII (FVIII) in patients with hemophilia A. Using FVIII-deficient mice, we compared the immunogenicity of different preparations of plasma-derived (pd) and recombinant (r) FVIII. Treatment of mice with p...

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Hlavní autoři:	Sandrine Delignat, Suryasarathi Dasgupta, Sébastien André, Ana-Maria Navarrete, Srinivas V. Kaveri, Jagadeesh Bayry, Marie-Hélène André, Sami Chtourou, Zéra Tellier, Sébastien Lacroix-Desmazes
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Ferrata Storti Foundation 2007-10-01
Edice:	Haematologica
On-line přístup:	https://haematologica.org/article/view/4611
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