Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms

The development of inhibitory antibodies to factor VIII is the most serious complication of replacement therapy in hemophilia A. Activation of the innate immune system during exposure to this protein contributes to inhibitor development. However, avoidance of factor VIII exposure during innate immun...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Maria T. Georgescu, Paul C. Moorehead, Alice S. van Velzen, Kate Nesbitt, Birgit M. Reipert, Katharina N. Steinitz, Maria Schuster, Christine Hough, David Lillicrap
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Ferrata Storti Foundation 2018-08-01
Цуврал:	Haematologica
Онлайн хандалт:	https://haematologica.org/article/view/8562
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!