Secondary follicles enable efficient germline mtDNA base editing at hard-to-edit site

Efficient germline mtDNA editing is required to construct disease-related animal models and future gene therapy. Recently, the DddA-derived cytosine base editors (DdCBEs) have made mitochondrial genome (mtDNA) precise editing possible. However, there still exist challenges for editing some mtDNA sit...

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Xehetasun bibliografikoak

Egile Nagusiak:	Qin Xie, Haibo Wu, Hui Long, Caiwen Xiao, Jiaxin Qiu, Weina Yu, Xueyi Jiang, Junbo Liu, Shuo Zhang, Qifeng Lyu, Lun Suo, Yanping Kuang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2024-06-01
Saila:	Molecular Therapy: Nucleic Acids
Gaiak:	MT: RNA/DNA Editing mitochondrial genome DdCBEs mtDNA gene editing TALENs
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S216225312400057X
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