Supplementation of Oocytes by Microinjection with Extra Copies of mtDNA Alters Metabolite Profiles and Interactions with Expressed Genes in a Tissue-Specific Manner

Mitochondrial DNA (mtDNA) supplementation can rescue poor oocyte quality and overcome embryonic arrest. Here, we investigated a series of sexually mature pigs generated through autologous and heterologous mtDNA supplementation. Brain, liver and heart tissues underwent metabolite profiling using gas...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Eryk Andreas, Alexander Penn, Takashi Okada, Justin C. St. John
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2024-11-01
Цуврал:	Biomolecules
Нөхцлүүд:	mtDNA mtDNA supplementation metabolite profile gene expression metabolic pathways brain
Онлайн хандалт:	https://www.mdpi.com/2218-273X/14/11/1477
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!