Bio-synthesis, purification and structural analysis of Cyclosporine-A produced by Tolypocladium inflatum with valorization of agro-industrial wastes

Abstract Cyclosporine A (CyA) holds significant importance as a strategic immunosuppressive drug for organ transplant patients. In this study, we aimed to produce pure and cost-effective Cyclosporine A (CyA) by fermenting a culture medium containing dairy sludge, using Tolypocladium inflatum PTCC 52...

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Bibliografische Detailangaben

Hauptverfasser:	Fereshteh Falah, Ali Samie, Seyed Ali Mortazavi, Abolghasem Danesh, Farideh Tabatabaei Yazdi, Mohammad Ramezani
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-05-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Cyclosporine Tolypocladium inflatum Purification Chemical structure
Online-Zugang:	https://doi.org/10.1038/s41598-024-63110-y
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