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Bio-synthesis, purification and structural analysis of Cyclosporine-A produced by Tolypocladium inflatum with valorization of agro-industrial wastes

Abstract Cyclosporine A (CyA) holds significant importance as a strategic immunosuppressive drug for organ transplant patients. In this study, we aimed to produce pure and cost-effective Cyclosporine A (CyA) by fermenting a culture medium containing dairy sludge, using Tolypocladium inflatum PTCC 52...

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Hlavní autoři: Fereshteh Falah, Ali Samie, Seyed Ali Mortazavi, Abolghasem Danesh, Farideh Tabatabaei Yazdi, Mohammad Ramezani
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-05-01
Edice:Scientific Reports
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On-line přístup:https://doi.org/10.1038/s41598-024-63110-y
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