Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain

Abstract Background Many lines of evidence suggest that accumulation of aggregated alpha-synuclein (αSYN) in the Parkinson’s disease (PD) brain causes infiltration of T cells. However, in which ways the stationary brain cells interact with the T cells remain elusive. Here, we identify astrocytes as...

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Главные авторы:	Jinar Rostami, Grammatiki Fotaki, Julien Sirois, Ropafadzo Mzezewa, Joakim Bergström, Magnus Essand, Luke Healy, Anna Erlandsson
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2020-04-01
Серии:	Journal of Neuroinflammation
Предметы:	Astrocytes T-cell infiltration MHC-II Antigen presentation Alpha-synuclein Parkinson’s disease
Online-ссылка:	http://link.springer.com/article/10.1186/s12974-020-01776-7
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