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Studies on alpha-synuclein and islet amyloid polypeptide interaction

Introduction: Parkinson’s disease and type 2 diabetes have both elements of local amyloid depositions in their pathogenesis. In Parkinson’s disease, alpha-synuclein (aSyn) forms insoluble Lewy bodies and Lewy neurites in brain neurons, and in type 2 diabetes, islet amyloid polypeptide (IAPP) compris...

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Principais autores: Ye Wang, Joakim Bergström, Martin Ingelsson, Gunilla T. Westermark
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Molecular Biosciences
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1080112/full
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