Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors

Histone deacetylases (HDACs) and sirtuins (SIRTs) are important epigenetic regulators of cancer pathways. There is a limited understanding of how transcriptional regulation of their genes is affected by chemotherapeutic agents, and how such transcriptional changes affect tumour sensitivity to drug t...

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主要な著者:	Julia Krushkal, Yingdong Zhao, Kyle Roney, Weimin Zhu, Alan Brooks, Deborah Wilsker, Ralph E. Parchment, Lisa M. McShane, James H. Doroshow
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis Group 2024-12-01
シリーズ:	Epigenetics
主題:	Histone deacetylase sirtuin dasatinib chemosensitivity HDAC5
オンライン･アクセス:	https://www.tandfonline.com/doi/10.1080/15592294.2024.2309824
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