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The role of HDAC3 in inflammation: mechanisms and therapeutic implications

Histone deacetylases (HDACs) are critical regulators of inflammatory gene expression, and the efficacy of pan-HDAC inhibitors has been implicated in various disease conditions. However, it remains largely unclear how HDACs precisely regulate inflammation. To this end, evaluating the isoform-specific...

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Hlavní autoři: Noah Watson, Sivaraman Kuppuswamy, William Luke Ledford, Sangeetha Sukumari-Ramesh
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-07-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1419685/full
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