The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging
Accumulation of somatic mutations in the mitochondrial genome (mtDNA) has long been proposed as a possible mechanism of mitochondrial and tissue dysfunction that occurs during aging. A thorough characterization of age-associated mtDNA somatic mutations has been hampered by the limited ability to det...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
eLife Sciences Publications Ltd
2023-02-01
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| سلاسل: | eLife |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://elifesciences.org/articles/83395 |
| الوسوم: |
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