CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.

The RNA-binding protein Tristetraprolin (TTP, ZFP36) functions as a tumor suppressor that impairs the development and disables the maintenance of MYC-driven lymphoma. In addition, other human cancers expressed reduced levels of TTP, suggesting that it may function as a tumor suppressor in several ma...

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Hlavní autoři:	Mohammad Fallahi, Antonio L Amelio, John L Cleveland, Robert J Rounbehler
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2014-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC4277357?pdf=render
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