Molecular regulation and therapeutic targeting of MYCN in neuroblastoma: a comprehensive review
MYCN amplification defines a highly aggressive subtype of neuroblastoma and is strongly associated with poor clinical outcomes. Due to the intrinsically disordered structure of the N-Myc protein, it remains largely undruggable. This review provides a comprehensive summary of the molecular regulatory...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2025-10-01
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| Серія: | Frontiers in Cell and Developmental Biology |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1683331/full |
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