Globoside Is an Essential Intracellular Factor Required for Parvovirus B19 Endosomal Escape

Human parvovirus B19 (B19V), like most parvoviruses, possesses phospholipase A2 (PLA2) activity, which is thought to mediate endosomal escape by membrane disruption. Here, we challenge this model and find evidence for a mechanism of B19V entry mediated by the glycosphingolipid globoside without endo...

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Detalhes bibliográficos

Principais autores:	Jan Bieri, Corinne Suter, Oliver Caliaro, Seraina Bartetzko, Cornelia Bircher, Carlos Ros
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-07-01
coleção:	Cells
Assuntos:	parvovirus B19 B19V globoside virus entry endosomal escape phospholipase A2
Acesso em linha:	https://www.mdpi.com/2073-4409/13/15/1254
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