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Stochastic Model of Virus–Endosome Fusion and Endosomal Escape of pH-Responsive Nanoparticles

In this paper, we set up a stochastic model for the dynamics of active Rab5 and Rab7 proteins on the surface of endosomes and the acidification process that govern the virus–endosome fusion and endosomal escape of pH-responsive nanoparticles. We employ a well-known cut-off switch model for Rab5 to R...

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Autores principales: Sergei Fedotov, Dmitri Alexandrov, Ilya Starodumov, Nickolay Korabel
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2022-01-01
Colección:Mathematics
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Acceso en línea:https://www.mdpi.com/2227-7390/10/3/375
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