Globoside Is an Essential Intracellular Factor Required for Parvovirus B19 Endosomal Escape

Human parvovirus B19 (B19V), like most parvoviruses, possesses phospholipase A2 (PLA2) activity, which is thought to mediate endosomal escape by membrane disruption. Here, we challenge this model and find evidence for a mechanism of B19V entry mediated by the glycosphingolipid globoside without endo...

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Principais autores:	Jan Bieri, Corinne Suter, Oliver Caliaro, Seraina Bartetzko, Cornelia Bircher, Carlos Ros
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-07-01
Serija:	Cells
Teme:	parvovirus B19 B19V globoside virus entry endosomal escape phospholipase A2
Online dostop:	https://www.mdpi.com/2073-4409/13/15/1254
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