Recent advances in targeting LRRK2 for Parkinson’s disease treatment

Abstract Parkinson’s disease (PD) is a neurodegenerative disease with severe movement problems. Current treatments mainly focus on symptom management by reducing dopaminergic pathways in the brain. Despite these therapies, ongoing disease progression undermines the effectiveness of prevalent approac...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Mahsa Karami, Pantea Majma Sanaye, Atousa Ghorbani, Roshanak Amirian, Pouya Goleij, Mehregan Babamohamadi, Zhila Izadi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-07-01
Цуврал:	Journal of Translational Medicine
Нөхцлүүд:	Parkinson’s disease LRRK2 Neurodegenerative diseases Autophagy PROTAC Mitochondrial dysfunction
Онлайн хандалт:	https://doi.org/10.1186/s12967-025-06354-0
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!