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Synthesis of 2,2,5-Trisubstituted Tetrahydrofurans by Ferrocenium-Catalyzed Dehydrative Diol Cyclization Reactions

A ferrocenium-catalyzed synthesis of trisubstituted tetrahydrofurans by dehydrative cyclization of diols is reported. Treatment of γ-phenyl-γ-butyrolactone or valerolactone with 2–3 equivalents of MeLi, <i>n</i>-BuLi, or PhLi yielded the corresponding substituted 1,4-butanediols in 41–86% yields. Su...

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Päätekijät: Cody D. Amann, Khushboo, Eike B. Bauer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2025-02-01
Sarja:Inorganics
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Linkit:https://www.mdpi.com/2304-6740/13/2/59
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