Synthesis of 2,2,5-Trisubstituted Tetrahydrofurans by Ferrocenium-Catalyzed Dehydrative Diol Cyclization Reactions
A ferrocenium-catalyzed synthesis of trisubstituted tetrahydrofurans by dehydrative cyclization of diols is reported. Treatment of γ-phenyl-γ-butyrolactone or valerolactone with 2–3 equivalents of MeLi, <i>n</i>-BuLi, or PhLi yielded the corresponding substituted 1,4-butanediols in 41–86% yields. Su...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
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MDPI AG
2025-02-01
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| Reeks: | Inorganics |
| Onderwerpen: | |
| Online toegang: | https://www.mdpi.com/2304-6740/13/2/59 |
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