USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma
Abstract Glioblastoma (GBM), a World Health Organization (WHO) grade IV glioma, is one of the most lethal brain tumors, with a poor prognosis and limited treatment options. Temozolomide (TMZ), a first-line chemotherapeutic agent, often proves ineffective due to resistance and toxicity associated wit...
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| Hoofdauteurs: | , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2025-08-01
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| Reeks: | Cell Death and Disease |
| Online toegang: | https://doi.org/10.1038/s41419-025-07969-3 |
| Tags: |
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