USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma
Abstract Glioblastoma (GBM), a World Health Organization (WHO) grade IV glioma, is one of the most lethal brain tumors, with a poor prognosis and limited treatment options. Temozolomide (TMZ), a first-line chemotherapeutic agent, often proves ineffective due to resistance and toxicity associated wit...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2025-08-01
|
| Collection: | Cell Death and Disease |
| Accès en ligne: | https://doi.org/10.1038/s41419-025-07969-3 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|