Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery

Abstract Background Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by increased levels of inflammation that primarily manifests in the joints. Macrophages act as key drivers for the progression of RA, contributing to the perpetuation of chronic inflammation and dysregulatio...

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Autors principals:	Molly Klimak, Amanda Cimino, Kristin L. Lenz, Luke E. Springer, Kelsey H. Collins, Natalia S. Harasymowicz, Nathan Xu, Christine T.N. Pham, Farshid Guilak
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-11-01
Col·lecció:	Arthritis Research & Therapy
Matèries:	Cell therapy Rheumatoid arthritis Designer cell Synthetic biology
Accés en línia:	https://doi.org/10.1186/s13075-024-03425-3
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