Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase.

Pericentric heterochromatin, while often considered as "junk" DNA, plays important functions in chromosome biology. It contributes to sister chromatid cohesion, a process mediated by the cohesin complex that ensures proper genome segregation during nuclear division. Long stretches of heterochromatin...

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Bibliografische Detailangaben

Hauptverfasser:	Raquel A Oliveira, Shaila Kotadia, Alexandra Tavares, Mihailo Mirkovic, Katherine Bowlin, Christian S Eichinger, Kim Nasmyth, William Sullivan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2014-10-01
Schriftenreihe:	PLoS Biology
Online-Zugang:	https://doi.org/10.1371/journal.pbio.1001962
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