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Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase.

Pericentric heterochromatin, while often considered as "junk" DNA, plays important functions in chromosome biology. It contributes to sister chromatid cohesion, a process mediated by the cohesin complex that ensures proper genome segregation during nuclear division. Long stretches of heterochromatin...

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Bibliografiset tiedot
Päätekijät: Raquel A Oliveira, Shaila Kotadia, Alexandra Tavares, Mihailo Mirkovic, Katherine Bowlin, Christian S Eichinger, Kim Nasmyth, William Sullivan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2014-10-01
Sarja:PLoS Biology
Linkit:https://doi.org/10.1371/journal.pbio.1001962
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