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Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase.

Pericentric heterochromatin, while often considered as "junk" DNA, plays important functions in chromosome biology. It contributes to sister chromatid cohesion, a process mediated by the cohesin complex that ensures proper genome segregation during nuclear division. Long stretches of heterochromatin...

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主要な著者: Raquel A Oliveira, Shaila Kotadia, Alexandra Tavares, Mihailo Mirkovic, Katherine Bowlin, Christian S Eichinger, Kim Nasmyth, William Sullivan
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2014-10-01
シリーズ:PLoS Biology
オンライン・アクセス:https://doi.org/10.1371/journal.pbio.1001962
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