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Characterizing Glycosylation of Adeno-Associated Virus Serotype 9 Capsid Proteins Generated from HEK293 Cells through Glycopeptide Mapping and Released Glycan Analysis

Recombinant adeno-associated viral (AAV) vectors have emerged as prominent gene delivery vehicles for gene therapy. AAV capsid proteins determine tissue specificity and immunogenicity and play important roles in receptor binding, the escape of the virus from the endosome, and the transport of the vi...

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Principais autores: Yu Zhou, Sonal Priya, Joseph Y. Ong
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2024-05-01
Series:Microorganisms
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Acceso en liña:https://www.mdpi.com/2076-2607/12/5/946
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