Impact of busulfan exposure stratification on transplant outcomes and immune reconstitution in children with severe aplastic anemia
BackgroundSevere aplastic anemia (SAA) is a life-threatening bone marrow failure disorder. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established curative treatment for pediatric patients with SAA. Busulfan, a key component of conditioning regimens, has a narrow therapeutic...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
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Frontiers Media S.A.
2026-09-01
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| Seri Bilgileri: | Frontiers in Pharmacology |
| Konular: | |
| Online Erişim: | https://www.frontiersin.org/articles/10.3389/fphar.2026.1897156/full |
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