Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms

Uncovering the regulators of cellular aging will unravel the complexity of aging biology and identify potential therapeutic interventions to delay the onset and progress of chronic, aging-related diseases. In this work, we systematically compared genesets involved in regulating the lifespan of Sacch...

Cur síos iomlán

Sonraí bibleagrafaíochta

Príomhchruthaitheoirí:	Mohammad Alfatah, Jolyn Jia Jia Lim, Yizhong Zhang, Arshia Naaz, Trishia Yi Ning Cheng, Sonia Yogasundaram, Nashrul Afiq Faidzinn, Jovian Jing Lin, Birgit Eisenhaber, Frank Eisenhaber
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	eLife Sciences Publications Ltd 2024-05-01
Sraith:	eLife
Ábhair:	cellular aging lifespan nutrient signaling target of rapamycin complex 1 mitochondria uncharacterized genes
Rochtain ar líne:	https://elifesciences.org/articles/92178
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!