Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms

Uncovering the regulators of cellular aging will unravel the complexity of aging biology and identify potential therapeutic interventions to delay the onset and progress of chronic, aging-related diseases. In this work, we systematically compared genesets involved in regulating the lifespan of Sacch...

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מידע ביבליוגרפי

Principais autores:	Mohammad Alfatah, Jolyn Jia Jia Lim, Yizhong Zhang, Arshia Naaz, Trishia Yi Ning Cheng, Sonia Yogasundaram, Nashrul Afiq Faidzinn, Jovian Jing Lin, Birgit Eisenhaber, Frank Eisenhaber
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	eLife Sciences Publications Ltd 2024-05-01
סדרה:	eLife
נושאים:	cellular aging lifespan nutrient signaling target of rapamycin complex 1 mitochondria uncharacterized genes
גישה מקוונת:	https://elifesciences.org/articles/92178
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!