Mechanistic models of asymmetric hand-over-hand translocation and nucleosome navigation by CMG helicase
Abstract Faithful replication of eukaryotic chromatin requires the CMG helicase to translocate directionally along single-stranded DNA (ssDNA) while unwinding double-stranded DNA (dsDNA) and navigating nucleosomes. However, the mechanism by which CMG achieves processive translocation and deals with...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-11-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-025-65232-x |
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