Chromosome length is constrained by spindle scaling to ensure faithful mitosis in mammals
Abstract Why eukaryotic genomes are universally divided among multiple chromosomes remains an unresolved question. Although yeast and mouse cells can tolerate chromosomal fusions without impairing viability, we show here that chromosome length in mammalian cells is constrained by a biophysical limit...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Nature
2026-01-01
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| Seri Bilgileri: | Molecular Systems Biology |
| Konular: | |
| Online Erişim: | https://doi.org/10.1038/s44320-026-00188-8 |
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