3-(((1<i>S</i>,3<i>S</i>)-3-((<i>R</i>)-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target Antidiabetic Agent

The chiral drug candidates have more effective binding affinities for their specific protein or receptor site for the onset of pharmacological action. Achieving all carbon stereopure compounds is not trivial in chemical synthesis. However, with the development of asymmetric organocatalysis, the synt...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Abdul Sadiq, Mater H. Mahnashi, Umer Rashid, Muhammad Saeed Jan, Mohammed Abdulrahman Alshahrani, Mohammed A. Huneif
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-05-01
Serie:	Molecules
Soggetti:	chiral synthesis antidiabetic molecular docking α-glucosidase α-amylase PTP1B and DPPH
Accesso online:	https://www.mdpi.com/1420-3049/27/10/3265
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!