3-(((1<i>S</i>,3<i>S</i>)-3-((<i>R</i>)-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target Antidiabetic Agent

The chiral drug candidates have more effective binding affinities for their specific protein or receptor site for the onset of pharmacological action. Achieving all carbon stereopure compounds is not trivial in chemical synthesis. However, with the development of asymmetric organocatalysis, the synt...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Abdul Sadiq, Mater H. Mahnashi, Umer Rashid, Muhammad Saeed Jan, Mohammed Abdulrahman Alshahrani, Mohammed A. Huneif
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2022-05-01
Цуврал:	Molecules
Нөхцлүүд:	chiral synthesis antidiabetic molecular docking α-glucosidase α-amylase PTP1B and DPPH
Онлайн хандалт:	https://www.mdpi.com/1420-3049/27/10/3265
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!