The Adhesion GPCR VLGR1/ADGRV1 Regulates the Ca²⁺ Homeostasis at Mitochondria-Associated ER Membranes

The very large G protein-coupled receptor (VLGR1, ADGRV1) is the largest member of the adhesion GPCR family. Mutations in VLGR1 have been associated with the human Usher syndrome (USH), the most common form of inherited deaf-blindness as well as childhood absence epilepsy. VLGR1 was previously found...

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Bibliografske podrobnosti

Principais autores:	Jacek Krzysko, Filip Maciag, Anna Mertens, Baran Enes Güler, Joshua Linnert, Karsten Boldt, Marius Ueffing, Kerstin Nagel-Wolfrum, Martin Heine, Uwe Wolfrum
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-09-01
Serija:	Cells
Teme:	adhesion GPCR mitochondria-associated ER membranes (MAM) mitochondria-endoplasmic reticulum contact sites (MERCS) Ca<sup>2+</sup> transient at ER and mitochondria Ca<sup>2+</sup> homeostasis
Online dostop:	https://www.mdpi.com/2073-4409/11/18/2790
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