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Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor

<p>Abstract</p> <p>Background</p> <p>Nuclear localization of proteolytically formed intracellular fragment of ErbB4 receptor tyrosine kinase has been shown to promote cell survival, and nuclear localization of ErbB4 receptor has been described in human breast cancer. Tumor necrosis factor alpha conv...

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Auteurs principaux: Tuittila Minna T, Henttinen Tiina, Olli Kaisa, Määttä Jorma A, Elenius Klaus, Salmivirta Markku
Format: Artigo
Langue:Inglês
Publié: BMC 2009-01-01
Collection:BMC Cell Biology
Accès en ligne:http://www.biomedcentral.com/1471-2121/10/5
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