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Proteolytic processing of ErbB4 in breast cancer.

ErbB4 is a receptor tyrosine kinase that can signal by a mechanism involving proteolytic release of intracellular and extracellular receptor fragments. Proteolysis-dependent signaling of ErbB4 has been proposed to be enhanced in breast cancer, mainly based on immunohistochemical localization of intr...

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Principais autores: Maija Hollmén, Ping Liu, Kari Kurppa, Hans Wildiers, Irene Reinvall, Thijs Vandorpe, Ann Smeets, Karen Deraedt, Tero Vahlberg, Heikki Joensuu, Daniel J Leahy, Patrick Schöffski, Klaus Elenius
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3382207?pdf=render
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