ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma

IntroductionMetastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic strategies. Applying chimeric antigen receptor (CAR) technology to natural killer (NK) cells may offe...

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Hlavní autoři:	Catrin Heim, Laura M. Moser, Herman Kreyenberg, Halvard B. Bonig, Torsten Tonn, Winfried S. Wels, Elise Gradhand, Evelyn Ullrich, Michael T. Meister, Marian Groot Koerkamp, Frank C. P. Holstege, Jarno Drost, Jan-Henning Klusmann, Peter Bader, Michael Merker, Eva Rettinger
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-08-01
Edice:	Frontiers in Immunology
Témata:	ERBB2 (HER2/neu) rhabdomyosarcoma chimeric antigen receptor xenograft cancer immunotherapy
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1228894/full
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