Epigenetic-mediated positive feedback loop facilitates the progression of lung adenocarcinoma

Summary: Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality. We performed multi-omics approaches on LUAD samples spanning different stages, establishing a detailed epigenetic landscape. We identified 1,416 regions characterized by hypo-DNA methylation and hyperchromatin a...

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Ngā kaituhi matua:	Yihang Cheng, Yifeng Luo, Tingting Hu, Qiaoling Ren, Li Xu, Tuo Yi, Yuan Tan, Wei Li, Xuxin Wang, Yaoxiang Sun, Mingzhi Chen, Zhonghua Shen, Bin Zhang, Youhuang Bai, Yue Tao, Zhihong Cao, Deqiang Sun
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2025-10-01
Rangatū:	iScience
Ngā marau:	Biological sciences Molecular biology Molecular mechanism of gene regulation
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2589004225016001
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!