Epigenetic-mediated positive feedback loop facilitates the progression of lung adenocarcinoma

Summary: Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality. We performed multi-omics approaches on LUAD samples spanning different stages, establishing a detailed epigenetic landscape. We identified 1,416 regions characterized by hypo-DNA methylation and hyperchromatin a...

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Detalles Bibliográficos

Principais autores:	Yihang Cheng, Yifeng Luo, Tingting Hu, Qiaoling Ren, Li Xu, Tuo Yi, Yuan Tan, Wei Li, Xuxin Wang, Yaoxiang Sun, Mingzhi Chen, Zhonghua Shen, Bin Zhang, Youhuang Bai, Yue Tao, Zhihong Cao, Deqiang Sun
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-10-01
Series:	iScience
Assuntos:	Biological sciences Molecular biology Molecular mechanism of gene regulation
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2589004225016001
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