Epigenetic-mediated positive feedback loop facilitates the progression of lung adenocarcinoma

Summary: Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality. We performed multi-omics approaches on LUAD samples spanning different stages, establishing a detailed epigenetic landscape. We identified 1,416 regions characterized by hypo-DNA methylation and hyperchromatin a...

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主要な著者:	Yihang Cheng, Yifeng Luo, Tingting Hu, Qiaoling Ren, Li Xu, Tuo Yi, Yuan Tan, Wei Li, Xuxin Wang, Yaoxiang Sun, Mingzhi Chen, Zhonghua Shen, Bin Zhang, Youhuang Bai, Yue Tao, Zhihong Cao, Deqiang Sun
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2025-10-01
シリーズ:	iScience
主題:	Biological sciences Molecular biology Molecular mechanism of gene regulation
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589004225016001
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