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Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy

Abstract This study investigated the effects of indirubin on autophagy and apoptosis in cervical cancer models, with a focus on elucidating the underlying molecular mechanisms. A xenograft tumor model in BALB/c-Nude mice and in vitro experiments using HeLa cell lines were employed. Indirubin treatme...

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Principais autores: Xiuchao Xie, Chang Liu, Xiaoling Liu, Lin Hou, Ya Zhang, Lin Huang, Weidong Peng, Yu Liu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2026-01-01
סדרה:Scientific Reports
נושאים:
Indirubin
Cervical cancer
HeLa
PI3K/AKT
MAPK
גישה מקוונת:https://doi.org/10.1038/s41598-026-35382-z
תגים: הוספת תג
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